CBD for Dog Anxiety: Top 6 Products According to a Veterinarian

Katelyn Son


Medically reviewed by

Ivana Crnec,DVM

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The products featured on this page are from our partners. We may be compensated for purchases made through these links. However, this does not influence our reviews and ratings. We independently research and test the products we recommend and our opinions are our own.

  • Best CBD Oil for Dog Anxiety: Honest Paws Calm CBD Oil   
    The perfect CBD for dog anxiety as it is of superior quality and efficacy. 
  • Best CBD Treats for Dog Anxiety: Honest Paws Calm CBD Treats 
    Best choice for tasty treats infused with CBD for dog anxiety. 
  • Most Affordable CBD Oil for Dog Anxiety: Simple Wag CBD Oil
    Affordability and high quality are the main features of this CBD for dog anxiety. 
  • Best Natural Ingredients: Four Leaf Rover CBD Oil
    Each ingredient in this CBD for dog anxiety is hand-picked and all-natural. 
  • Best CBD Subscribe and Save Option: Charlotte’s Web CBD
    Budget-friendly policies that make the CBD for dog anxiety easily accessible for all pet owners. 
  • Extra Strength CBD Treats for  Dog Anxiety: Penelope’s Bloom CBD Treats
    Oven-baked and full-spectrum treats enriched with CBD for dog anxiety. 

Does CBD Really Help Dogs With Anxiety?


Yes, CBD for dog anxiety is helpful. In fact, CBD oil provides stress relief in various situations, from separation anxiety and loud noises like fireworks and thunderstorms, to vet visits and car rides. 

Because of the calming effect, recent studies suggest that cannabidiol is the new “potential treatment for anxiety disorders.” Plus, pet CBD is not psychoactive and cannot make your dog “high.”

CBD for dog anxiety is a natural remedy extracted from the Cannabis plant or, more precisely, from hemp. As hemp extracts, pet CBD products are perfectly safe for dogs. However, the use of CBD for dog anxiety is not FDA-approved. 

How does CBD For Dog Anxiety Work?

CBD (cannabidiol) works by interacting with the endocannabinoid system (ECS). The ECS is present in all mammals and consists of endocannabinoids that are synthesized in the body, cannabinoid receptors (CB1 and CB2), and enzymes. 

When the endocannabinoids bind with the receptors, they regulate different body functions like sleep, memory, inflammation, mood, immunity, appetite, metabolism, pain, etc. The goal of the ECS is to maintain homeostasis, which is a state of health and balance. Once the endocannabinoid fulfills their role, they are broken down by the enzymes. 

CBD works by replacing the natural endocannabinoids and binding with the receptors, thus supporting the ECS. Since mood is one of the functions regulated by the ECS, it is easy to see the connection between CBD and anxiety relief. 

Will CBD Calm My Dog Down?

Yes, CBD for dog anxiety may calm your pet down. CBD supports calmness and relaxation by changing the brain chemistry and improving the sensitivity to serotonin, which is the feel-good hormone. 

In addition to managing stress and anxiety, CBD for dog anxiety has other health benefits. For example, CBD relieves chronic pain, supports the immune system, and can be used in the treatment of epilepsy. In a nutshell, CBD boosts the dog’s health and emotional wellbeing. 

What are the Benefits of CBD for Dog Anxiety?

CBD helps dogs with anxiety on several levels. In fact, CBD is popularly described as a potential treatment for anxiety disorders. Below we list the science supporting this description.

CBD Helps Promote Relaxation. The leading theory is that CBD works by modulating the brain’s response to serotonin and making the receptors in the brain more susceptible to this chemical. Serotonin is the so-called “feel-good” hormone responsible for happiness and relaxation. In rat models, regular use of CBD has an anti-panic effect, thus promoting relaxation.  

CBD Supports Normal Emotional Balance. As mentioned, CBD works through the ECS, which is responsible for balancing the nervous system. During an anxiety attack, the nerve cells are frantically firing out, leading to a chemical disbalance. This is where the ECS steps in – it slows down the electrical misfiring and returns the chemicals in the body to baseline. In simple words, supplementing with CBD for dog anxiety, it is like hitting the reset button. 

CBD Calms Fears From Environmentally-Induced Stress. Dogs feel scared when there are inexplicable changes in their environment – loud noises, house remodeling, moving to a different home, or new family members. CBD helps relieve general anxiety and can help with specific environmental stressors. For example, CBD for dog anxiety may help in the management of noise phobias

CBD Helps Maintain Contentment During Separation. As an increasingly common behavioral issue, separation anxiety is a concerning modern dog ailment. Although triggered by fear of being alone on its basis, separation anxiety triggers the same changes as any other form of anxiety. Therefore, CBD for dog anxiety may help promote relaxation and improve sleep in anxious pets. 

The Best CBD for Dog Anxiety Reviewed

Pet owners find it hard to choose the best CBD pet product for their dogs. After all, there are so many different CBD brands and supplements on the pet care market. To make things simpler, we have chosen and reviewed the best CBD for dog anxiety products. 

Honest Paws Calm CBD Oil


Get it on Honest Paws

Summary: When thinking about CBD oil for dogs with anxiety, Honest Paws should be your first choice because it is definitely our number one. The Honest Paws Calm CBD is a full-spectrum CBD oil and is made of organic hemp plant. It is available in different strengths and is easy to use. Their CBD oil includes calming ingredients including chamomile.


  • Full-spectrum CBD formula
  • With calming chamomile oil 
  • CO2 extracted and organic 
  • Third-party lab tests are available 


  • COA does not include pesticides 

Review: Dog owners say their dogs “do not bark or pace as much when left alone” after using the Honest Paws Calm oil and that it is a “great product.” All in all, Honest Paws is the best CBD for dog anxiety. 

What are Customers Saying about Honest Paws Calm CBD Oil?

“We love it! Remi has been a lot calmer, less agitated, and seems super happy! Thank you so much for having such a great product! She seems like she’s back to her good old self. Thank you Honest Paws. We have recommended your product to several of our friends who said they were going to get some for their pups too!”
– Alexson H.

“The CBD calm has done wonders for my Frenchie. She suffers from separation anxiety until we started her on the calm CBD. Now she is so much better, simply amazing.”
– Cris S.

Honest Paws Calm CBD Treats


Get it on Honest Paws

Summary: From positive reviews and success stories to media mentions and 5-star ratings, Honest Paws is a vet-approved and recommended brand. The Honest Paws CBD Calm treats are available in two textures (soft chews and bites), two dog-friendly flavors (peanut butter and poultry), and enriched with calming ingredients like L-theanine and tryptophan. 


  • With full-spectrum hemp oil
  • Non-GMO and free from additives  
  • Different textures and flavors
  • Added calming ingredients 


  • Only one strength available 

Review: Pet owners say their dogs are “so much more relaxed ” after using the CBD Calm treats. They describe them as “high-quality treats” and say that they “really work.” All in all, Honest Paws offers the best CBD treats for dogs with anxiety. 

What are Customers Saying about Honest Paws Calm CBD Treats?

“Helps keep our dog from getting overly excited. He had a hard time not jumping on people when they come over or knocking down our 2-year old when he gets excited which is often. And when he’s in that state he just doesn’t listen. The CBD oil with calm bites keeps him more steady throughout the day. He’s had no negative reactions.”
– Crissy S.

“We choose to live remotely on a lake in Georgia. A round trip drive to town takes two hours, so with shopping we are gone 4 to 6 hours about twice a week. Most days the weather is too hot so I have to leave my small dog at home. The Bites clearly lower his anxiety level. No more scratching the door frame or trying to dig underneath it. Makes me feel better to lower his anxiety. I definitely recommend this product.”
– Rebecca F.

Simple Wag CBD Oil


Get it on Simple Wag

Summary: Simple Wag offers an efficient yet affordable solution for one of the most common modern dog issues – anxiety. The enriched full-spectrum CBD formula by Simple Wag is the perfect option for dogs with anxiety problems. Plus, the budget-friendly price makes this CBD product easily accessible. 


  • Full-spectrum CBD formula 
  • Excellent cost to potency ratio 
  • Lab-tested and USDA certified 
  • Practical and eco-friendly bottle


  • Limited selection of CBD products 

Review: Pet owners say the Simple Wag is a “good product to have on hand.” They say the oil “works wonders,” and their “dogs like it.” All in all, Simple Wag is the most affordable CBD for dog anxiety. 

Four Leaf Rover CBD Oil


Get it on The Natural Dog Store

Summary: Dogs Naturally’s products are made of natural and premium-quality ingredients. The Four Leaf Rover CBD is the perfect combo of full-spectrum CBD oil and human-grade MCT oil as a carrier. Available in various potencies, there is a Four Leaf Rover option for all anxious dogs, regardless of their size. 


  • High-quality CBD oil with a coconut oil carrier 
  • Rich in terpenes, flavonoids, and fatty acids 
  • No allergens, pesticides, and heavy metals 
  • Certificate of Analysis available 


  • No dog-friendly flavors 

Review: Dog owners say the Four Leaf Rover is an “excellent product” and “works immediately.” They say the oil makes their dogs “calm and happy.” All in all, Four Leaf Rover has the best natural ingredients in CBD oil for dogs with anxiety. 

Charlotte’s Web CBD Treats

Charlottes Web - Calm

Get it on Charlotte’s Web

Summary: Charlotte’s Web is a CBD brand that believes in the health benefits of natural cannabinoids. The Charlotte’s Web CBD treats are made of full-spectrum hemp extract and added calming ingredients (valerian root, passionflower extract, and chamomile). Each treat contains 2.5 mg of CBD, thus being perfect for small dogs with anxiety issues. 


  • With full-spectrum CBD oil 
  • Added calming botanical blend 
  • No gluten, soy, and additives 
  • Made from US grown hemp


  • Not cost-effective for large dogs 

Review: Dog owners say The Charlotte’s Web treats “do the trick” and “they would definitely buy them again.” All in all, Charlotte’s Web has the best subscribe and save options for CBD treats for dogs with anxiety. 

Penelope’s Bloom CBD Treats



Get it on Penelope’s Bloom

Summary: Penelope’s Bloom is a small CBD brand that cares for both pets and the environment. The Penelope’s Bloom CBD treats are all-natural and specifically made for dogs with stress and anxiety. They feature full-spectrum hemp oil and have 20 mg of CBD per treat, thus being perfect for large and giant anxious dogs. 


  • With full-spectrum hemp
  • Plant-based ingredients 
  • Oven-baked and tasty 
  • Potent and fast-acting 


  • Unresponsive customer service 

Review: Pet owners say the Penelope’s Bloom CBD treats bring their pets “to the most mellow place ” and that they “really work.” All in all, Penelope’s Bloom offers the best extra-strength CBD treats for dogs with anxiety. 

How can I Use CBD for Dog Anxiety?

Compared to CBD oil, dog CBD treats are more practical and can be used on the go. Treats often feature chicken or bacon flavors and are therefore much easier to administer to dogs.

However, they are usually available in one potency making the dosing a bit more challenging, and it takes their effects longer to kick in.

On the other hand, the CBD oil kicks in much faster and is more cost-effective, especially if your anxious dog is big or giant-sized. The only issue with tinctures is the bitter aftertaste making them hard to give to dogs with picky appetites. 

Regardless of whether you choose CBD oil or CBD dog treats, it is paramount to ensure you are buying CBD products made exclusively for pets. Human CBD products contain tetrahydrocannabinol (THC) which is toxic to pets. 

Also, check with the vet before using. In general, CBD for dog anxiety is safe and can be used in conjunction with other medications. However, as dog owners, you need to err on the side of caution and double-check. 

How Much CBD Should I Give My Dog for Anxiety?

You can give your dog between 1 and 5 mg of CBD oil per 10 pounds of body weight per day for anxiety. The CBD for dog anxiety dose guidelines are not set in stone, and finding the CBD amount that works best for your dog takes some trial and error. 

We suggest starting with a small amount of CBD and increasing the dose gradually as your dog gets used to the CBD supplement. To ensure your dog is stress-free 24/7, you should use CBD regularly and split the daily CBD dose into two servings. 

After you have the dose, if you accidentally give an extra dropper of oil, do not worry – dogs cannot overdose on CBD

Giving your dog too much CBD oil will probably make it sleep off the effects. It is also possible for your pet to develop some minor side effects like dry mouth, increased thirst, drowsiness, lowered blood pressure, and diarrhea.  

How Long Does it Take for CBD to Work on Dogs for Anxiety?

It usually takes between 30 and 45 minutes for CBD to start working and calm an anxious dog. Generally speaking, CBD oil works faster, while CBD dog treats take longer. 

This is because soft chews and bites contain more ingredients and need more time for digestion. If you need fast results, it is best to give CBD oil sublingually (under the dog’s tongue). 

Best Seller
Honest Paws Calm Soft Chews
10/10Our Score
  • Honest Paws Calm Soft Chews can help settle your furry friend’s nerves in as little as one hour.
  • Honest Paws Calm line is specifically formulated to promote relaxation in stressed out dogs.
  • Made with organic, full-spectrum hemp oil and other all-natural ingredients, Honest Paws Calm line is the perfect all-natural remedy for stress.

How does CBD Compare to Alternative Dog Anxiety Treatments?

The most benign medication option for anxiety treatment is Benadryl which is actually an antihistamine. However, not all dogs will experience a satisfactory level of anxiety relief, and Benadryl is not a long-term solution. 

The second most popular choice is diazepam. According to one study, diazepam was described as very effective only in 24% of the cases and was more efficient in dogs with noise phobia than separation anxiety. 58% of the dog owners decided to discontinue the diazepam use due to side effects like sedation followed by agitation and increased activity, ataxia, increased appetite, and aggression. 

In more severe cases, the mainstream for managing anxiety is drugs like Prozac (Fluoxetine), Trazodone, Xanax (Alprazolam), and Clomipramine (Anafranil). However, although efficient, these meds are likely to cause serious side effects.     

On the other hand, CBD for dog anxiety is efficient, safe, and rarely triggers side effects. Even if there are any side effects, they are mild, transient, and easily manageable. According to the World Health Organization report on cannabidiol, “CBD is generally well-tolerated, with a good safety profile.” 

What are the Signs & Symptoms of Dog Anxiety?


Canine anxiety affects over 88% of the dog population, thus being the most common mental illness in dogs. From separation anxiety through fear of loud noises to old-fashioned PTSD, the list of stressors in dogs is long and complex.

Causes of Anxiety in Dogs

Based on the exact trigger, there are four different types of anxiety in dogs. Here are the most common anxiety causes in dogs: 

  • Separation anxiety
  • Age-related anxiety
  • Post-traumatic stress
  • Fear-related anxiety

Signs Your Dog has Anxiety

Below we have listed some of the most common anxiety signs and symptoms in dogs.

  • Aggression
  • Constant pacing
  • Depression and lethargy
  • Excessive or frantic barking
  • Lack of appetite or overeating 
  • Lip licking and drooling 
  • Repetitive behaviors
  • Urinating or defecating in the house.

If your dog is exhibiting these signs and symptoms of anxiety, it is best advised to schedule a veterinary visit to make sure CBD is the best option for your dog’s treatment.