Best CBD For Dog Seizures 2021 – Top 6 Products Reviewed

Katelyn Son


Medically reviewed by

Ivana Crnec,DVM

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See our advertising disclosure.

Best CBD for Dog Seizures at a Glance

  • Best CBD Oil for Dog Seizures: Honest Paws CBD Oil     
    Number one CBD for dog seizures due to unmatched qualities and features. 
  • Best CBD Treats: Honest Paws CBD Treats     
    Tasty and condition-specific treats infused with CBD for dog seizures. 
  • Best Price: Simple Wag     
    Simple yet efficient full-spectrum CBD for dog seizures formula at an available price. 
  • All Natural Ingredients: Four Leaf Rover     
    CBD for dog seizures made with organic hemp and all-natural added ingredients. 
  • Highest Potency Treats: Penelope’s Bloom
    Delicious and easy-to-use treats with CBD for dog seizures. 
  • Best Flavor Range: Petly CBD
    CBD for dog seizures available in an array of dog-friendly flavors. 

Will CBD Help My Dog’s Seizures?

Will CBD Help My Dog's Seizures

Yes, CBD oil can help dogs with seizures. CBD for dog seziures may help decrease the seizure activity’s frequency and intensity. Plus, as a holistic remedy, high-quality CBD for dog seizures is perfectly safe and can be combined with traditional anti-seizure medications. 

CBD (cannabidiol) is a cannabis plant extract that interacts with the endocannabinoid system (ECS). The ECS is responsible for maintaining a state of homeostasis and consists of endocannabinoids, cannabinoid receptors (CB1 receptors and CB2 receptors), and enzymes. CBD replaces the endocannabinoids and binds with the endocannabinoid receptors. 

Seizures are accompanied by two issues, uncontrolled distribution of signals between neurons and inflammation of the brain tissues (neuroinflammation). Through the ECS, CBD can help with both of them. However, pet owners need to be aware that CBD is not approved by the FDA for use in veterinary medicine. 

Research on CBD Oil for Dog Seizures

CBD for dog seizures is a relatively new product on the pet care market but already showing promising results in the management of dog seizures and epilepsy. The AKC Canine Health Foundation is currently funding a clinical trial on the “Efficacy of Cannabidiol for the Treatment of Canine Epilepsy.” 

The AKC Epilepsy Research Initiative works to understand the condition of seizures better. With their cannabidiol CBD clinical trial, the goal is to determine if medical professionals and dog owners can use CBD to treat seizure frequency. Participants have stated the positive findings – a “potential to improve the quality and length of life for dogs with uncontrolled epilepsy and add a much-needed tool for veterinarians in the treatment of canine epilepsy.”

Plus, during a clinical trial with sixteen dogs with seizures, McGrath found that 89% of the dogs in the CBD group had a reduction in seizure frequency, while the seizure activity remained the same in the placebo group. “It’s really exciting that perhaps we can start looking at CBD in the future as an alternative to existing anticonvulsive drugs,” McGrath said. 

The Best CBD for Dog Seizures

Dog owners can be easily confused by the number of different CBD  brands and products on the market. To make things simpler, we have reviewed the best CBD for dog seizures. 

Honest Paws CBD Oil

Honest Paws CBD Oil

Get it on Honest Paws

Summary: The Honest Paws CBD line of products is not just veterinarian-approved, but according to the 113K happy customers, it is also pet parents-approved. The oil is rich in various cannabinoids with proven anti-seizure properties. Plus, it is available in different potencies for all dogs. 


  • Human-grade and full-spectrum 
  • From organically grown hemp plants 
  • Sourced and manufactured in the US 
  • Certificate of analysis available 


  • The COA does not test for pesticides  

Review: Pet parents say the Honest Paws CBD oil is a “secret weapon,” and it “really works.” They also say their dogs like the oil. All in all, Honest Paws offers the best CBD for dog seizures.  

Honest Paws CBD Treats

Honest paws Well Bites

Get it on Honest Paws

Summary: Honest Paws is the top trustworthy and reliable CBD brand in the US. Offering a wide range of condition-specific CBD products, the brand has something for every dog. The CBD treats are made with full-spectrum hemp and are ideal for picky eaters with seizures. 


  • With full-spectrum, organic CBD oil 
  • Added health-boosting ingredients 
  • Dog-friendly flavors and textures 
  • No artificial ingredients and additives


  • High-demand followed by low stock

Review: Pet owners say their dogs “honestly like” the Honest Paws CBD dog treats. They also mention they are “easy to use” and “efficient.” All in all, Honest Paws offers the best CBD dog treats for seizures.  

Simple Wag CBD Oil


Get it on Simple Wag

Summary: Simple Wag believes that every dog deserves to wag its tail with happiness. And to ensure as much wagging tail as possible, the brand offers an efficient yet affordable anti-seizures tool, efficient in reducing pain and managing inflammation. 


  • Full-spectrum CBD oil
  • Rich in vitamins, omegas, and antioxidants 
  • Lab-tested and USDA certified 
  • Comes in an eco-friendly bottle 


  • Limited selection of CBD oils 

Review: Pet parents say the Simple Wag CBD oil “works wonders.” They are also happy with the affordability of the supplement. All in all, Simple Wag offers the best price for CBD for dog seizures. 

Four Leaf Rover CBD Oil


Get it on The Natural Dog Store

Summary: Changing the world one dog at a time truly is possible with the Dogs Naturally CBD products. The Four Leaf Rover CBD oil by Dogs Naturally is full-spectrum and with potent anti-inflammation features suitable for dogs with neuroinflammation and epilepsy.  


  • Full-spectrum CBD oil with different potencies 
  • Organic and all-natural ingredients 
  • Extracted with supercritical CO2
  • Certificate of Analysis available 


  • Occasional low stock due to high demand 

Review: Dog owners say the Four Leaf Rover CBD oil is “really powerful” and “works miracles.” The careful selection of natural ingredients is a bonus. All in all, Four Leaf Rover offers the best natural ingredients in CBD for dog seizures. 

Penelope’s Bloom CBD Treats


Get it on Penelope’s Bloom

Summary: Penelope’s Bloom is a pet CBD brand that cares and it uses sustainable ingredients, recycles materials, and donates to pet shelters. The Penelope’s Bloom CBD treats are perfect for big dogs with seizures as they contain 20 mg of cannabidiol per treat. 


  • Made of full-spectrum hemp CBD oil
  • Extra healthy and oven-baked 
  • With excellent CBD potency
  • Available in an eco-friendly package 


  • Poorer customer service than similar brands 

Review: Dog owners say the Penelope’s Bloom CBD treats “make a difference.” They are also happy with the cost-effectiveness of the product. All in all, Penelope’s Bloom has the CBD treats with the highest potency for dogs with seizures. 

Petly CBD Treats

Petly CBD dog treats

Get it on Petly CBD

Summary: Despite being new on the market, the Petly CBD oil made it on the top 5 list for dogs with seizures. This is due to the quality, safety, and efficacy of its products in managing canine epilepsy. Namely, Petly CBD takes the science behind its products seriously.


  • Various CBD products  
  • 100% organic, vegan, and gluten-free 
  • Excellent customer service and policies 
  • Donates for pets in need 


  • With broad-spectrum hemp oil 

Review: Pet owners say the Petly CBD oil is “convenient” and “easy to use.” They are delighted by the array of choices. All in all, Petly CBD has the best flavor range of CBD oils for dog seizure management. 

How to Use CBD for Dog Seizures

CBD for dog seizures comes in various forms, from fast-acting CBD oils or tinctures to easy-to-use CBD treats. They all contain cannabidiol as the main active ingredient. However, there are specific differences. 

For example, CBD oil exerts its effects quickly, but it can be harder to use, especially in dogs with fussy eating habits. CBD oils have an earthy and bitter taste dogs are not very fond of. CBD treats however, take more time to work but are tasty, and dogs love them. Also, CBD treats are more expensive, particularly for large and giant dogs. 

The good news is that the use of CBD oil does not exclude the use of CBD treats. Namely, you can use CBD oil when in need of fast results and tasty CBD treats when on the go. 

Finally, when using CBD for dog seizures, make sure the product is made exclusively for dogs. CBD products made for humans contain THC (tetrahydrocannabinol), which is toxic to dogs. 

How Much CBD Do I Give My Dog for Seizures?

You should give your dog between 1 and 5 mg of CBD per 10 pounds of body weight. Finding the right CBD for dog seizures dose for managing your dog’s seizures will take trial and error. Different dogs respond differently, and there are variations based on the intensity of epileptic seizures.

The general rule of the thumb is to start small and gradually increase the dose as your dog gets used to the CBD product. 

If you accidentally give too much CBD for dog seizures, do not worry – dogs cannot overdose on CBD oil. However, you can expect mild and temporary side effects such as dry mouth, increased thirst, slight lethargy, lowered blood pressure, and diarrhea

Finally, we should note that it is important to consult with your veterinarian or veterinary neurologist before adding CBD to your dog’s seizure management plan. This is because CBD can interact with certain over-the-counter and prescription medications. 

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Honest Paws Well CBD Oil for Dogs
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The Benefits of CBD For Dogs With Seizures

A groundbreaking clinical trial conducted at the Colorado State University by dr. Stephanie McGrath showed that CBD helps manage seizures in 90% of the cases. Now that we have your attention let’s have a closer look at the benefits of CBD oil for dogs with seizures.

CBD can Help Minimize Severity and Frequency of Seizures. Studies show that CBD can decrease the seizure frequency and the severity of the episodes. This is because CBD has anti-epileptic and anticonvulsant features. Interestingly, even synthetic CBD versions have the same ability to manage the frequency and intensity of seizures.   

CBD Promotes Normal Healthy Brain Activity. One important aspect of seizure development is neuroinflammation. This inflammation is triggered by electrical outbursts and contributes to the future worsening of the episode. CBD has pronounced anti-inflammatory properties which can control neuroinflammation, thus promoting healthy brain activity.   

CBD Supports Normal Nerve Conduction. Seizures are associated with abnormal outbursts of electrical activity in the brain. Studies show that CBD could modulate neuron excitability by affecting certain receptors within the dog’s brain. This will result in normal and controlled electrical conduction between the nerves.

CBD Helps Maintain Normal Nervous System Function. As mentioned, the effects of CBD for dog seizures management stem from its ability to boost and support the functioning of the endocannabinoid system. The ECS promotes and maintains normal nervous system function, meaning CBD can help with this.

Can CBD Help With the Pain from Dog Seizures?

Yes, CBD for dog seizures may also help with the pain. Namely, CBD helps provide pain relief and can also help manage the anxiety and stress following episodes of seizure activity. 

On top of managing pain and anxiety, CBD for dog seizures will support the dog’s immune system, improve its mood, and in simple words, positively affect the dog’s overall health and quality of life. 

Treatment Options for Dog Seizures

The conventional management of canine epilepsy is based on several registered meds. Here is a list of the commonly used anticonvulsant drugs: 

  • Phenobarbital
  • Levetiracetam
  • Zonisamide
  • Diazepam 
  • Potassium bromide.  

However, there are some concerns about these drugs. For example, the official anti-epileptic drugs (AEDs) are borrowed from human medicine and have frequent and serious side effects, and dogs buildup tolerance after long-term use of AEDs. Plus, not all patients respond to these medications meaning they are not always 100% efficient. 

In comparison, CBD for dog seizures is safe and has fewer side effects, does not build tolerance in long-term use, and is efficient in decreasing both the frequency and intensity of seizures. 

What is the Best Treatment for Seizures in Dogs?

The best treatment for seizures in dogs is multimodal – includes a combination of mainstream medications, holistic supplements, and diet modifications. 

For example, you can use a traditional anti-epileptic drug in conjunction with CBD. CBD for dog seizures will potentiate the effects of the drug and allow using a smaller dosage, thus decreasing the risk of side effects. The diet changes will help restore chemical balance in the brain and help prevent seizure activity.

However, the anti-seizure strategy is not universal and each dog requires an individually tailored approach. Therefore, you need to consult with a veterinary neurologist and determine the best management for your dog’s case. 

Dog Seizures: Signs & Symptoms


If your pet is diagnosed with canine epilepsy, you are not alone since this is the most common neurologic disorder in canines. Seizures are defined as uncontrolled outbursts of electrical brain activity. 

Seizures are singular events, while epilepsy manifests with frequent seizures. As DVM Jerry Klein, Chief Veterinary Officer at AKC (American Kennel Club), explains, it must be noted that seizures are not a disease – they are a symptom. 

Causes of Seizures in Dogs

Seizures are most commonly caused by idiopathic epilepsy, which is an inherited condition typical for certain dog breeds (Beagles, Labrador Retrievers, Border Collies, German Shepherds).

Other causes of canine seizures include:

  • Traumatic head injury 
  • Brain inflammations and tumors
  • Infectious diseases
  • Strokes
  • Metabolic or electrolyte imbalances
  • Poison ingestion
  • Anemia
  • Kidney and liver disease.  

Signs Your Dog has Seizures and What to do

The exact clinical manifestation depends on the seizure type. In general, there are three types of seizures: 

  • Psychomotor seizures cause behavior changes like tail-chasing or biting the air.
  • Focal Seizures affect one side of the body and are localized.
  • Grand Mal Seizures are generalized and usually make the dog hit the floor in convulsions. 

Considering the reverse manifestation, here is a list of the possible dog seizure signs and symptoms:

  • Chomping
  • Collapsing to the floor
  • Drooling
  • Foaming at the mouth
  • Incontinence (urinary or fecal)
  • Jerking
  • Loss of consciousness
  • Muscle twitching
  • Paddling motion with legs (if your dog has fallen on his side)
  • Whole-body stiffening.

There is no first aid for seizuring dogs – you just need to make sure your pet does not hit its head from hard surfaces. Once the episode is over, the dog will be confused and scared. In such a case, you need to be comforting and support your dog.